Added annotations

c/aguilar-2017.mmt

@@ -359,9 +359,11 @@ dot(uis) = (inf - uis) / tau
     inf = 1 / (1 + exp((V + 5 [mV]) / 5 [mV]))
     tau = 5800 [ms] / (1 + exp((V + 80 [mV]) / -11 [mV]))
         in [ms]
-gKur = 0.005 [nS/pF] + 0.05 [nS/pF] / (1 + exp((V - 15 [mV]) / -13 [mV]))
+gKur_base = 0.005 [nS/pF]
+    in [nS/pF]
+    label g_Kur
+gKur = gKur_base * (1 + 10 / (1 + exp((V - 15 [mV]) / -13 [mV])))
     in [nS/pF]
-    desc: Maximal IKur conductance
 IKur = gKur * ua^3 * uif * uis * (V - nernst.EK)
     in [A/F]
     label I_Kur

c/annotations.md

@@ -14,6 +14,8 @@
 - `g_CaL`, a variable that can be scaled up and down to scale `I_CaL`.
 - `I_Kr`, the rapid delayed rectifier potassium current.
 - `g_Kr`, a variable that can be scaled up or down to scale `I_Kr`.
+- `I_Kur`, the ultra-rapid potassium or sustained outward current.
+- `g_Kur`, a variable that can be scaled up or down to scale `I_Kur`.
 
 - `Ca_i`, the bulk cytosolic calcium concentration
 - `K_o`, the external (bulk, buffer, not cleft) potassium concentration

c/bai-2018.mmt

@@ -259,8 +259,10 @@ dot(s) = (inf - s) / tau
 use membrane.V, nernst.EK
 IKur = gKur * x * y * (V - EK)
     in [A/F]
+    label I_Kur
 gKur = 0.045 [mS/uF]
     in [mS/uF]
+    label g_Kur
 dot(x) = (inf - x) / tau
     inf = 1 / (1 + exp((V + 6 [mV]) / -8.6 [mV]))
     tau = 9 [ms] / (1 + exp((V + 6 [mV]) / 12 [mV])) + 0.5 [ms]

c/courtemanche-1998.mmt

@@ -368,9 +368,11 @@ dot(ui) = (inf - ui) / tau
         beta = 1 [1/ms] / exp((V - 158 [mV]) / -16 [mV])  # CellML uses -16, Paper uses 16. But graph in paper shows -16 (and KQ10=1).
             in [1/ms]
     inf = 1 / (1 + exp((V - 99.45 [mV]) / 27.48 [mV]))
-gKur = 0.005 [nS/pF] + 0.05 [nS/pF] / (1 + exp((V - 15 [mV]) / -13 [mV]))
+gKur_base = 0.005 [nS/pF]
+    in [nS/pF]
+    label g_Kur
+gKur = gKur_base * (1 + 10 / (1 + exp((V - 15 [mV]) / -13 [mV])))
     in [nS/pF]
-    desc: Maximal IKur conductance
 IKur = gKur * ua^3 * ui * (V - nernst.EK)
     in [A/F]
     label I_Kur

c/ellinwood-2017.mmt

@@ -470,6 +470,7 @@ gKur = gKur_base * (1 - 0.5 * mode.AF) * (1 + 2 * mode.ISO)
     in [mS/uF]
 gKur_base = 0.045 [mS/uF] * 1.36
     in [mS/uF]
+    label g_Kur
 a = 2.65 [1/ms] * exp((V - 75.9 [mV]) / 70 [mV])
     in [1/ms]
 b = 2.65 [1/ms] * exp((V - 75.9 [mV]) / 70 [mV]) * exp(-(V + 20.9 [mV]) / 10 [mV]) / (1 + 0.3 * exp(-(V + 20.9 [mV]) / 10 [mV]))

c/grandi-2011.mmt

@@ -419,6 +419,7 @@ gKur = gKur_base * (1 - 0.5 * mode.AF) * (1 + 2 * mode.ISO) * (1 + 0.2 * mode.RA
     in [mS/uF]
 gKur_base = 0.045 [mS/uF]
     in [mS/uF]
+    label g_Kur
 dot(r) = (inf - r) / tau
     inf = 1 / (1 + exp((V + 6 [mV]) / -8.6 [mV]))
     tau = 9 [ms] / (1 + exp((V + 5 [mV]) / 12 [mV])) + 0.5 [ms]

c/koivumaki-2011.mmt

@@ -219,6 +219,7 @@ dot(s) = (inf - s) / tau
 gKur = 0.89 * 2.75 [nS]
     in [nS]
     comment: Decreased by ~11% in Maleckar et al.
+    label g_Kur
 IKur = gKur * r * s * (V - nernst.EK)
     in [pA]
     label I_Kur

c/maleckar-2009.mmt

@@ -276,6 +276,7 @@ dot(i) = (inf - i) / tau
         in [s]
 gKur = 2.25 [nS]
     in [nS]
+    label g_Kur
 IKur = gKur * a * i * (V - rev.EK)
     in [pA]
 
@@ -292,6 +293,7 @@ dot(pa) = (inf - pa) / tau
 pi = 1 / (1 + exp((V + 55 [mV]) / 24 [mV]))
 gKr = 0.5 [nS]
     in [nS]
+    label g_Kr
 IKr = gKr * pa * pi * (V - rev.EK)
     in [pA]
 

c/ni-2017.mmt

@@ -451,6 +451,7 @@ dot(i) = (inf - i) / tau
 
 gKur = 0.006398 [nS/pF] * 0.9 * if(af.af == 1, 0.5, 1)
     in [nS/pF]
+    label g_Kur
 IKur = Cm * gKur * (4.5128 + 1.899769 / (1 + exp((V - 20.5232 [mV]) / -8.26597 [mV]))) * (1 - BO - BC) * a * i * (V - nernst.EK)
     in [pA]
 

c/nygren-1998.mmt

@@ -285,6 +285,7 @@ dot(s) = (inf - s) / tau
         in [s]
 g_sus = 2.75 [nS]
     in [nS]
+    label g_Kur
 Isus = g_sus * r * s * (V - rev.EK)
     in [pA]
 

c/voigt-2013.mmt

@@ -433,6 +433,7 @@ dot(s) = (inf - s) / tau
         in [ms]
 gKur = (1 - 0.5 * cell.AF) * 0.045 [mS/uF]  # Corresponds to LA Grandi parameters
     in [mS/uF]
+    label g_Kur
 IKur = gKur * r * s * (V - nernst.EK)
     in [A/F]
     label I_Kur