A tutorial and reference design for machine learning inference on FPGA-based frame grabber devices in high-throughput imaging applications. This tutorial leverages the hls4ml package and the CustomLogic toolkit to deploy neural networks to Euresys frame grabber devices. Refer to hls4ml-frame-grabber-tutorial.ipynb to get started. See part9_YOLO_frame_grabbers.ipynb for a more advanced guide on implementing a YOLO model and taking advantage of the suite of optimizations hls4ml provides.