SelectSim

The goal of SelectSim package is to implement the methodology to infer inter-dependencies between functional alterations in cancer. SelectSim estimates the expected number of mutations in a given gene and a given sample from the mutation frequency of the gene, f(g), and the tumor mutation burden (TMB) of the sample, $\mu$(t). These values can be estimated within specific mutation and tumor subsets, to account for heterogeneous tumor types, tissue specificities, and distinct mutational processes

SelectSim Method

Installation

• You can install the development version of SelectSim from GitHub with:

# install.packages("devtools")
devtools::install_github("CSOgroup/SelectSim",dependencies = TRUE, build_vignettes = TRUE)

• For more details on installation refer to INSTALLATION

Example

Check the the Vignettes folder or visit website

Who do I talk to?

• For any bugs or feature support in using SelectSim, please use the issue tracker.
• For any other question related to SelectSim, please contact Prof Giovanni Ciriello (giovanni.ciriello@unil.ch) or Arvind Iyer (arvind.iyer@unil.ch).