diff --git a/samples/drivers/adc/adc_sequence/boards/lp_em_cc2340r5.conf b/samples/drivers/adc/adc_sequence/boards/lp_em_cc2340r5.conf
new file mode 100644
index 000000000000..65f176fd23b9
--- /dev/null
+++ b/samples/drivers/adc/adc_sequence/boards/lp_em_cc2340r5.conf
@@ -0,0 +1 @@
+CONFIG_SEQUENCE_RESOLUTION=12
diff --git a/samples/drivers/adc/adc_sequence/boards/lp_em_cc2340r5.overlay b/samples/drivers/adc/adc_sequence/boards/lp_em_cc2340r5.overlay
new file mode 100644
index 000000000000..9e4c9fce369c
--- /dev/null
+++ b/samples/drivers/adc/adc_sequence/boards/lp_em_cc2340r5.overlay
@@ -0,0 +1,34 @@
+/*
+ * Copyright (c) 2024 BayLibre, SAS
+ *
+ * SPDX-License-Identifier: Apache-2.0
+ */
+
+#include <zephyr/dt-bindings/adc/adc.h>
+
+/ {
+	aliases {
+		adc0 = &adc0;
+	};
+};
+
+&adc0 {
+	status = "okay";
+
+	#address-cells = <1>;
+	#size-cells = <0>;
+
+	channel@2 {
+		reg = <2>;
+		zephyr,gain = "ADC_GAIN_1";
+		zephyr,reference = "ADC_REF_VDD_1";
+		zephyr,acquisition-time = <ADC_ACQ_TIME_DEFAULT>;
+	};
+
+	channel@8 {
+		reg = <8>;
+		zephyr,gain = "ADC_GAIN_1";
+		zephyr,reference = "ADC_REF_VDD_1";
+		zephyr,acquisition-time = <ADC_ACQ_TIME_DEFAULT>;
+	};
+};