README.md

The Neural Simulation Tool - NEST with NcN lab changes

Cloned from original repository nest-simulator

---

Changes:

1. Extracellular recording from hh_cond_exp_traub neuron model

Theoretical material

The theoretical information was taken from article (Harilal P, 2016) Computational Modeling of Single Neuron Extracellular Electric Potentials and Network Local Field Potentials using LFPsim

With NEURON, the transmembrane ionic currents in multi-compartmental models can be calculated by summing up all active currents estimated using extracellular mechanism from NEURON as implemented in LFPsim

I_transmemberane = I_ionic + C_m * ∂V_m / ∂t

Where, I_ionic represent the ionic currents and C_m * ∂V_m / ∂t represent the capacitive current.

NEST realisation

The formula was extended for NEST hh_cond_exp_traub neuron model

EC = I_Na + I_K + I_L + I_syn_exc + I_syn_inh + C_m * node.P_.delta_Vm / Time::get_resolution().get_ms()

Where (pseudo-code):

node.P_.delta_Vm = V_m[n] - V_m[n-1]

Results

The NEST results was compared with results of (Bradley J, 2009)

2. Pre-synaptic inhibition

Theoretical material

NEST realisation

Results