#HIMA: High-dimensional Mediation Analysis

HIMA is an R package for estimating and testing high-dimensional mediation effects in genomic/epigenomic studies.

Installation

In R console,

## Install REMP
library(devtools)
install_github("YinanZheng/HIMA",
               dependencies=TRUE)
               
## If SSL cert verification failure
library(RCurl)
library(httr)
set_config( config( ssl_verifypeer = 0L ) )
install_github("YinanZheng/HIMA",
               dependencies=TRUE)

##Citation:

Zhang H, Zheng Y, Zhang Z, Gao T, Joyce B, Yoon G, Zhang W, Schwartz J, Just A, Colicino E, Vokonas P, Zhao L, Lv J, Baccarelli A, Hou L, Liu L. Estimating and Testing High-dimensional Mediation Effects in Epigenetic Studies. Bioinformatics. 2016. DOI: http://dx.doi.org/10.1093/bioinformatics/btw351. PubMed PMID: 27357171.

##Contact package maintainer: Yinan Zheng

Email: y-zheng@northwestern.edu