diff --git a/.circleci/config.yml b/.circleci/config.yml
index f304262d43..e48d899e9c 100644
--- a/.circleci/config.yml
+++ b/.circleci/config.yml
@@ -108,6 +108,12 @@ jobs:
       - image: circleci/python:3.5
         environment:
           TOXENV: py35-native-state-byzantium
+  py35-native-state-constantinople:
+    <<: *common
+    docker:
+      - image: circleci/python:3.5
+        environment:
+          TOXENV: py35-native-state-constantinople
   py35-native-state-frontier:
     <<: *common
     docker:
@@ -175,6 +181,12 @@ jobs:
       - image: circleci/python:3.6
         environment:
           TOXENV: py36-native-state-byzantium
+  py36-native-state-constantinople:
+    <<: *common
+    docker:
+      - image: circleci/python:3.6
+        environment:
+          TOXENV: py36-native-state-constantinople
   py36-native-state-frontier:
     <<: *common
     docker:
@@ -205,6 +217,12 @@ jobs:
       - image: circleci/python:3.6
         environment:
           TOXENV: py36-rpc-state-byzantium
+  py36-rpc-state-constantinople:
+    <<: *common
+    docker:
+      - image: circleci/python:3.6
+        environment:
+          TOXENV: py36-rpc-state-constantinople
   py36-rpc-state-frontier:
     <<: *common
     docker:
@@ -340,11 +358,13 @@ workflows:
       - py37-beacon
 
       - py36-native-state-byzantium
+      - py36-native-state-constantinople
       - py36-native-state-frontier
       - py36-native-state-homestead
       - py36-native-state-eip150
       - py36-native-state-eip158
       - py36-rpc-state-byzantium
+      - py36-rpc-state-constantinople
       - py36-rpc-state-frontier
       - py36-rpc-state-homestead
       - py36-rpc-state-eip150
@@ -364,6 +384,7 @@ workflows:
       - py36-beacon
 
       - py35-native-state-byzantium
+      - py35-native-state-constantinople
       - py35-native-state-frontier
       - py35-native-state-homestead
       - py35-native-state-eip150
diff --git a/eth/__init__.py b/eth/__init__.py
index 21a35c0c6b..0da2b8e042 100644
--- a/eth/__init__.py
+++ b/eth/__init__.py
@@ -21,7 +21,7 @@
 #
 #  Ensure we can reach 1024 frames of recursion
 #
-EVM_RECURSION_LIMIT = 1024 * 10
+EVM_RECURSION_LIMIT = 1024 * 12
 sys.setrecursionlimit(max(EVM_RECURSION_LIMIT, sys.getrecursionlimit()))
 
 
diff --git a/eth/tools/fixtures/helpers.py b/eth/tools/fixtures/helpers.py
index 06c0c15b3d..0340f9e32e 100644
--- a/eth/tools/fixtures/helpers.py
+++ b/eth/tools/fixtures/helpers.py
@@ -40,6 +40,7 @@
     BaseVM,
 )
 from eth.vm.forks import (
+    ConstantinopleVM,
     ByzantiumVM,
     TangerineWhistleVM,
     FrontierVM,
@@ -123,6 +124,10 @@ def chain_vm_configuration(fixture: Dict[str, Any]) -> Iterable[Tuple[int, Type[
         return (
             (0, ByzantiumVM),
         )
+    elif network == 'Constantinople':
+        return (
+            (0, ConstantinopleVM),
+        )
     elif network == 'FrontierToHomesteadAt5':
         HomesteadVM = BaseHomesteadVM.configure(support_dao_fork=False)
         return (
diff --git a/eth/vm/logic/system.py b/eth/vm/logic/system.py
index 7852e046ee..bb75c5f723 100644
--- a/eth/vm/logic/system.py
+++ b/eth/vm/logic/system.py
@@ -20,12 +20,9 @@
     ceil32,
 )
 from eth.vm import mnemonics
-from eth.vm.computation import (
-    BaseComputation
-)
-from eth.vm.opcode import (
-    Opcode,
-)
+from eth.vm.computation import BaseComputation
+from eth.vm.message import Message
+from eth.vm.opcode import Opcode
 
 from .call import max_child_gas_eip150
 
@@ -193,13 +190,16 @@ def __call__(self, computation: BaseComputation) -> None:
             code=call_data,
             create_address=contract_address,
         )
+        self.apply_create_message(computation, child_msg)
 
+    def apply_create_message(self, computation: BaseComputation, child_msg: Message) -> None:
         child_computation = computation.apply_child_computation(child_msg)
 
         if child_computation.is_error:
             computation.stack_push(0)
         else:
-            computation.stack_push(contract_address)
+            computation.stack_push(child_msg.storage_address)
+
         computation.return_gas(child_computation.get_gas_remaining())
 
 
@@ -240,3 +240,22 @@ def generate_contract_address(self,
             stack_data.salt,
             call_data
         )
+
+    def apply_create_message(self, computation: BaseComputation, child_msg: Message) -> None:
+        # We need to ensure that creation operates on empty storage **and**
+        # that if the initialization code fails that we revert the account back
+        # to its original state root.
+        snapshot = computation.state.snapshot()
+
+        computation.state.account_db.delete_storage(child_msg.storage_address)
+
+        child_computation = computation.apply_child_computation(child_msg)
+
+        if child_computation.is_error:
+            computation.state.revert(snapshot)
+            computation.stack_push(0)
+        else:
+            computation.state.commit(snapshot)
+            computation.stack_push(child_msg.storage_address)
+
+        computation.return_gas(child_computation.get_gas_remaining())
diff --git a/fixtures b/fixtures
index 95a3092038..420f443477 160000
--- a/fixtures
+++ b/fixtures
@@ -1 +1 @@
-Subproject commit 95a309203890e6244c6d4353ca411671973c13b5
+Subproject commit 420f443477caa8516f1f9ee8122fafc3415c0f34
diff --git a/tests/conftest.py b/tests/conftest.py
index e298dc4d39..4c439532e7 100644
--- a/tests/conftest.py
+++ b/tests/conftest.py
@@ -23,10 +23,13 @@
 # Uncomment this to have logs from tests written to a file.  This is useful for
 # debugging when you need to dump the VM output from test runs.
 """
+import datetime
+import logging
+import os
+from eth.tools.logging import TRACE_LEVEL_NUM
+
 @pytest.yield_fixture(autouse=True)
 def _file_logging(request):
-    import datetime
-    import os
 
     logger = logging.getLogger('eth')
 
diff --git a/tests/json-fixtures/test_blockchain.py b/tests/json-fixtures/test_blockchain.py
index 1aa902890a..5d03c8a3dc 100644
--- a/tests/json-fixtures/test_blockchain.py
+++ b/tests/json-fixtures/test_blockchain.py
@@ -45,6 +45,11 @@
     # The result is in conflict with the yellow-paper:
     # * https://github.com/ethereum/py-evm/pull/1224#issuecomment-418800369
     ('GeneralStateTests/stRevertTest/RevertInCreateInInit_d0g0v0.json', 'RevertInCreateInInit_d0g0v0_Byzantium'),  # noqa: E501
+    ('GeneralStateTests/stRevertTest/RevertInCreateInInit_d0g0v0.json', 'RevertInCreateInInit_d0g0v0_Constantinople'),  # noqa: E501
+    # The CREATE2 variant seems to have been derived from the one above - it, too,
+    # has a "synthetic" state, on which py-evm flips.
+    # * https://github.com/ethereum/py-evm/pull/1181#issuecomment-446330609
+    ('GeneralStateTests/stCreate2/RevertInCreateInInitCreate2_d0g0v0.json', 'RevertInCreateInInitCreate2_d0g0v0_Constantinople'),  # noqa: E501
 }
 
 
@@ -84,8 +89,6 @@ def fixture(fixture_data):
         fixture_key,
         normalize_blockchain_fixtures,
     )
-    if fixture['network'] == 'Constantinople':
-        pytest.skip('Constantinople VM rules not yet supported')
     return fixture
 
 
diff --git a/tests/json-fixtures/test_state.py b/tests/json-fixtures/test_state.py
index bac660cfca..18b246922b 100644
--- a/tests/json-fixtures/test_state.py
+++ b/tests/json-fixtures/test_state.py
@@ -28,12 +28,14 @@
     HomesteadVM,
     SpuriousDragonVM,
     ByzantiumVM,
+    ConstantinopleVM,
 )
 from eth.vm.forks.tangerine_whistle.state import TangerineWhistleState
 from eth.vm.forks.frontier.state import FrontierState
 from eth.vm.forks.homestead.state import HomesteadState
 from eth.vm.forks.spurious_dragon.state import SpuriousDragonState
 from eth.vm.forks.byzantium.state import ByzantiumState
+from eth.vm.forks.constantinople.state import ConstantinopleState
 
 from eth.rlp.headers import (
     BlockHeader,
@@ -144,6 +146,7 @@ def expand_fixtures_forks(all_fixtures):
     # The result is in conflict with the yellow-paper:
     # * https://github.com/ethereum/py-evm/pull/1224#issuecomment-418800369
     ('stRevertTest/RevertInCreateInInit.json', 'RevertInCreateInInit', 'Byzantium', 0),
+    ('stRevertTest/RevertInCreateInInit.json', 'RevertInCreateInInit', 'Constantinople', 0),
 }
 
 
@@ -245,6 +248,10 @@ def get_prev_hashes_testing(self, last_block_hash, db):
     __name__='ByzantiumStateForTesting',
     get_ancestor_hash=get_block_hash_for_testing,
 )
+ConstantinopleStateForTesting = ConstantinopleState.configure(
+    __name__='ConstantinopleStateForTesting',
+    get_ancestor_hash=get_block_hash_for_testing,
+)
 
 FrontierVMForTesting = FrontierVM.configure(
     __name__='FrontierVMForTesting',
@@ -271,6 +278,11 @@ def get_prev_hashes_testing(self, last_block_hash, db):
     _state_class=ByzantiumStateForTesting,
     get_prev_hashes=get_prev_hashes_testing,
 )
+ConstantinopleVMForTesting = ConstantinopleVM.configure(
+    __name__='ConstantinopleVMForTesting',
+    _state_class=ConstantinopleStateForTesting,
+    get_prev_hashes=get_prev_hashes_testing,
+)
 
 
 @pytest.fixture
@@ -287,7 +299,7 @@ def fixture_vm_class(fixture_data):
     elif fork_name == ForkName.Byzantium:
         return ByzantiumVMForTesting
     elif fork_name == ForkName.Constantinople:
-        pytest.skip("Constantinople VM has not been implemented")
+        return ConstantinopleVMForTesting
     elif fork_name == ForkName.Metropolis:
         pytest.skip("Metropolis VM has not been implemented")
     else:
diff --git a/tests/json-fixtures/test_transactions.py b/tests/json-fixtures/test_transactions.py
index 26d7a18395..3051bb2cdc 100644
--- a/tests/json-fixtures/test_transactions.py
+++ b/tests/json-fixtures/test_transactions.py
@@ -28,6 +28,9 @@
 from eth.vm.forks.byzantium.transactions import (
     ByzantiumTransaction
 )
+from eth.vm.forks.constantinople.transactions import (
+    ConstantinopleTransaction
+)
 
 from eth_typing.enums import (
     ForkName
@@ -92,7 +95,7 @@ def fixture_transaction_class(fixture_data):
     elif fork_name == ForkName.Byzantium:
         return ByzantiumTransaction
     elif fork_name == ForkName.Constantinople:
-        pytest.skip("Constantinople Transaction class has not been implemented")
+        return ConstantinopleTransaction
     elif fork_name == ForkName.Metropolis:
         pytest.skip("Metropolis Transaction class has not been implemented")
     else:
diff --git a/tox.ini b/tox.ini
index 86e48878c8..e84b3d86c4 100644
--- a/tox.ini
+++ b/tox.ini
@@ -3,7 +3,7 @@ envlist=
     py{35,36}-{core,database,transactions,vm,native-blockchain}
     py{36}-{benchmark,p2p,trinity,lightchain_integration,beacon}
     py{36}-rpc-blockchain
-    py{36}-rpc-state-{frontier,homestead,eip150,eip158,byzantium,quadratic}
+    py{36}-rpc-state-{frontier,homestead,eip150,eip158,byzantium,constantinople,quadratic}
     py{35,36}-native-state-{frontier,homestead,eip150,eip158,byzantium,constantinople,metropolis}
     py37-{core,trinity,trinity-integration,beacon}
     py{35,36}-lint
@@ -32,6 +32,8 @@ commands=
     beacon: pytest {posargs:tests/beacon/}
     # The following test seems to consume a lot of memory. Restricting to 3 processes reduces crashes
     rpc-state-byzantium: pytest -n3 {posargs:tests/trinity/json-fixtures-over-rpc/test_rpc_fixtures.py -k 'GeneralStateTests and not stQuadraticComplexityTest and Byzantium'}
+    # Uncomment the next line + modify test_rpc_fixtures.py when Constantinople is included in the mainnet config
+    # rpc-state-constantinople: pytest -n3 {posargs:tests/trinity/json-fixtures-over-rpc/test_rpc_fixtures.py -k 'GeneralStateTests and not stQuadraticComplexityTest and Constantinople'}
     rpc-state-quadratic: pytest {posargs:tests/trinity/json-fixtures-over-rpc/test_rpc_fixtures.py -k 'GeneralStateTests and stQuadraticComplexityTest'}
     transactions: pytest {posargs:tests/json-fixtures/test_transactions.py}
     vm: pytest {posargs:tests/json-fixtures/test_virtual_machine.py}