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poolqtl

Code to detect allele specific binding (ASB) of RNA binding proteins (RBP) to RNA from pooled (from multiple individuals) RNA immunoprecipation & sequencing (RIP-seq) data.

Analysis pipeline is in /src. Underlying code is in the package /src/poolQTL.

TODO

  • Compare sQTL enrichment for different models (beta and Gaussian models, Peter's mixture model) and different significance thresholds for calling ASB.
  • Add more features to sQTL enrichment analysis (e.g. distance to junction/cluster?)
  • Package poolQTL by making setup.py and specifying requirements.

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