Include environment variables in interpreter info caching

crates/uv-cache/src/lib.rs

@@ -18,7 +18,6 @@ use uv_fs::{cachedir, directories, LockedFile};
 use uv_normalize::PackageName;
 use uv_pypi_types::ResolutionMetadata;
 
-pub use crate::by_timestamp::CachedByTimestamp;
 #[cfg(feature = "clap")]
 pub use crate::cli::CacheArgs;
 use crate::removal::Remover;
@@ -27,7 +26,6 @@ pub use crate::wheel::WheelCache;
 use crate::wheel::WheelCacheKind;
 
 mod archive;
-mod by_timestamp;
 #[cfg(feature = "clap")]
 mod cli;
 mod removal;
@@ -1034,7 +1032,7 @@ impl CacheBucket {
             Self::SourceDistributions => "sdists-v8",
             Self::FlatIndex => "flat-index-v2",
             Self::Git => "git-v0",
-            Self::Interpreter => "interpreter-v4",
+            Self::Interpreter => "interpreter-v5",
             // Note that when bumping this, you'll also need to bump it
             // in `crates/uv/tests/it/cache_clean.rs`.
             Self::Simple => "simple-v15",

crates/uv-python/src/interpreter.rs

@@ -1,10 +1,11 @@
 use std::borrow::Cow;
 use std::env::consts::ARCH;
+use std::ffi::OsString;
 use std::fmt::{Display, Formatter};
-use std::io;
 use std::path::{Path, PathBuf};
 use std::process::{Command, ExitStatus};
 use std::sync::OnceLock;
+use std::{env, io};
 
 use configparser::ini::Ini;
 use fs_err as fs;
@@ -14,7 +15,7 @@ use serde::{Deserialize, Serialize};
 use thiserror::Error;
 use tracing::{debug, trace, warn};
 
-use uv_cache::{Cache, CacheBucket, CachedByTimestamp, Freshness};
+use uv_cache::{Cache, CacheBucket, CacheEntry, Freshness};
 use uv_cache_info::Timestamp;
 use uv_cache_key::cache_digest;
 use uv_fs::{write_atomic_sync, PythonExt, Simplified};
@@ -24,6 +25,7 @@ use uv_pep508::{MarkerEnvironment, StringVersion};
 use uv_platform_tags::Platform;
 use uv_platform_tags::{Tags, TagsError};
 use uv_pypi_types::{ResolverMarkerEnvironment, Scheme};
+use uv_static::EnvVars;
 
 use crate::implementation::LenientImplementationName;
 use crate::platform::{Arch, Libc, Os};
@@ -713,6 +715,42 @@ pub enum InterpreterInfoError {
     },
 }
 
+/// Environment variables that can change the values of [`InterpreterInfo`].
+#[derive(Debug, Deserialize, Serialize, Clone, PartialEq, Eq)]
+struct PythonEnvVars {
+    /// `PYTHONHOME` overrides `sys.prefix`.
+    pythonhome: Option<OsString>,
+    /// `PYTHONPATH` adds to `sys.path`.
+    pythonpath: Option<OsString>,
+    /// `PYTHONSAFEPATH` influences `sys.path`.
+    pythonsafepath: Option<OsString>,
+    /// `PYTHONPLATLIBDIR` influences `sys.path`.
+    pythonplatlibdir: Option<OsString>,
+    /// `PYTHONNOUSERSITE` influences `sys.path`.
+    pythonnousersite: Option<OsString>,
+    /// `PYTHONUSERBASE` influences `sys.path`.
+    pythonuserbase: Option<OsString>,
+    /// `APPDATA` influences `sys.path` through the user site packages (windows).
+    appdata: Option<OsString>,
+    /// `HOME` influences `sys.path` through the user site packages (unix).
+    home: Option<OsString>,
+}
+
+impl PythonEnvVars {
+    fn from_env() -> Self {
+        Self {
+            pythonhome: env::var_os(EnvVars::PYTHONHOME),
+            pythonpath: env::var_os(EnvVars::PYTHONPATH),
+            pythonsafepath: env::var_os(EnvVars::PYTHONSAFEPATH),
+            pythonplatlibdir: env::var_os(EnvVars::PYTHONPLATLIBDIR),
+            pythonnousersite: env::var_os(EnvVars::PYTHONNOUSERSITE),
+            pythonuserbase: env::var_os(EnvVars::PYTHONUSERBASE),
+            appdata: env::var_os(EnvVars::APPDATA),
+            home: env::var_os(EnvVars::HOME),
+        }
+    }
+}
+
 #[derive(Debug, Deserialize, Serialize, Clone)]
 struct InterpreterInfo {
     platform: Platform,
@@ -732,6 +770,18 @@ struct InterpreterInfo {
     gil_disabled: bool,
 }
 
+#[derive(Debug, Deserialize, Serialize, Clone)]
+struct CachedInterpreterInfo {
+    /// Information about a Python interpreter at a path.
+    data: InterpreterInfo,
+    /// The last modified timestamp of the Python interpreter path.
+    ///
+    /// It is ctime on unix.
+    timestamp: Timestamp,
+    /// Environment variables that can influence the other keys used for cache invalidation.
+    env_vars: PythonEnvVars,
+}
+
 impl InterpreterInfo {
     /// Return the resolved [`InterpreterInfo`] for the given Python executable.
     pub(crate) fn query(interpreter: &Path, cache: &Cache) -> Result<Self, Error> {
@@ -869,36 +919,10 @@ impl InterpreterInfo {
             })?;
 
         // Read from the cache.
-        if cache
-            .freshness(&cache_entry, None)
-            .is_ok_and(Freshness::is_fresh)
+        if let Some(value) =
+            Self::read_and_validate_cache(executable, cache, &cache_entry, modified)
         {
-            if let Ok(data) = fs::read(cache_entry.path()) {
-                match rmp_serde::from_slice::<CachedByTimestamp<Self>>(&data) {
-                    Ok(cached) => {
-                        if cached.timestamp == modified {
-                            trace!(
-                                "Cached interpreter info for Python {}, skipping probing: {}",
-                                cached.data.markers.python_full_version(),
-                                executable.user_display()
-                            );
-                            return Ok(cached.data);
-                        }
-
-                        trace!(
-                            "Ignoring stale interpreter markers for: {}",
-                            executable.user_display()
-                        );
-                    }
-                    Err(err) => {
-                        warn!(
-                            "Broken interpreter cache entry at {}, removing: {err}",
-                            cache_entry.path().user_display()
-                        );
-                        let _ = fs_err::remove_file(cache_entry.path());
-                    }
-                }
-            }
+            return Ok(value);
         }
 
         // Otherwise, run the Python script.
@@ -914,15 +938,82 @@ impl InterpreterInfo {
             fs::create_dir_all(cache_entry.dir())?;
             write_atomic_sync(
                 cache_entry.path(),
-                rmp_serde::to_vec(&CachedByTimestamp {
+                rmp_serde::to_vec(&CachedInterpreterInfo {
                     timestamp: modified,
                     data: info.clone(),
+                    env_vars: PythonEnvVars::from_env(),
                 })?,
             )?;
         }
 
         Ok(info)
     }
+
+    /// If a cache entry for the Python interpreter exists and it's fresh, return it.
+    fn read_and_validate_cache(
+        executable: &Path,
+        cache: &Cache,
+        cache_entry: &CacheEntry,
+        modified: Timestamp,
+    ) -> Option<InterpreterInfo> {
+        if !cache
+            .freshness(cache_entry, None)
+            .is_ok_and(Freshness::is_fresh)
+        {
+            return None;
+        }
+
+        let data = match fs::read(cache_entry.path()) {
+            Ok(data) => data,
+            Err(err) if err.kind() == io::ErrorKind::NotFound => {
+                return None;
+            }
+            Err(err) => {
+                warn!(
+                    "Broken interpreter cache entry at {}, removing: {err}",
+                    cache_entry.path().user_display()
+                );
+                let _ = fs_err::remove_file(cache_entry.path());
+                return None;
+            }
+        };
+
+        let cached = match rmp_serde::from_slice::<CachedInterpreterInfo>(&data) {
+            Ok(cached) => cached,
+            Err(err) => {
+                warn!(
+                    "Broken interpreter cache entry at {}, removing: {err}",
+                    cache_entry.path().user_display()
+                );
+                let _ = fs_err::remove_file(cache_entry.path());
+                return None;
+            }
+        };
+
+        if cached.timestamp != modified {
+            trace!(
+                "Ignoring stale cached interpreter info for: `{}`",
+                executable.user_display()
+            );
+            return None;
+        }
+
+        if cached.env_vars != PythonEnvVars::from_env() {
+            trace!(
+                "Ignoring cached interpreter info due to changed environment variables for: `{}`",
+                executable.user_display()
+            );
+            return None;
+        }
+
+        trace!(
+            "Cached interpreter info for Python {}, skipping probing: `{}`",
+            cached.data.markers.python_full_version(),
+            executable.user_display()
+        );
+
+        Some(cached.data)
+    }
 }
 
 /// Find the Python executable that should be considered the "base" for a virtual environment.

crates/uv-static/src/env_vars.rs

@@ -649,4 +649,22 @@ impl EnvVars {
     ///
     /// This is a quasi-standard variable, described e.g. in `ncurses(3x)`.
     pub const COLUMNS: &'static str = "COLUMNS";
+
+    /// Overrides `sys.prefix`.
+    pub const PYTHONHOME: &'static str = "PYTHONHOME";
+
+    /// Don't prepend a potentially unsafe path to `sys.path`.
+    pub const PYTHONSAFEPATH: &'static str = "PYTHONSAFEPATH";
+
+    /// Overrides `sys.platlibdir`.
+    pub const PYTHONPLATLIBDIR: &'static str = "PYTHONPLATLIBDIR";
+
+    /// Don't add the user site packages to `sys.path`.
+    pub const PYTHONNOUSERSITE: &'static str = "PYTHONNOUSERSITE";
+
+    /// Overrides `site.USER_BASE`.
+    pub const PYTHONUSERBASE: &'static str = "PYTHONUSERBASE";
+
+    /// The base path for user site packages on Windows.
+    pub const APPDATA: &'static str = "APPDATA";
 }