diff --git a/wsdiscovery/threaded.py b/wsdiscovery/threaded.py
index 0b309e5..b33de81 100644
--- a/wsdiscovery/threaded.py
+++ b/wsdiscovery/threaded.py
@@ -121,7 +121,15 @@ def _createMulticastOutSocket(self, addr, ttl):
         else:
             iface = int(addr.scope_id)
 
-        sock.setsockopt(ip_proto, self._get_multicast(), iface)
+        try:
+            sock.setsockopt(ip_proto, self._get_multicast(), iface)
+        except OSError as e:
+            logger.warning(
+                "Interface for %s does not support "
+                "multicast flags or is not UP: OSError %s",
+                addr,
+                e
+            )
 
         return sock