diff --git a/docs/faq.rst b/docs/faq.rst
index 9a06519..47f6ae6 100644
--- a/docs/faq.rst
+++ b/docs/faq.rst
@@ -78,7 +78,7 @@ This can also be easily run using the Docker image, which already contains all o
 
 .. code-block:: bash
 
-    docker run -it --rm -v $PWD:$PWD -w $PWD aertslab/pyscenic:0.10.3 \
+    docker run -it --rm -v $PWD:$PWD -w $PWD aertslab/pyscenic:0.12.1 \
         python add_visualization.py \
             --loom_input auc_mtx.loom \
             --loom_output scenic_visualize.loom \
diff --git a/docs/installation.rst b/docs/installation.rst
index cc0adf2..81cacae 100644
--- a/docs/installation.rst
+++ b/docs/installation.rst
@@ -72,7 +72,7 @@ A command line version of the tool is included. This tool is available after pro
     $ pyscenic -h
     usage: pyscenic [-h] {grn,add_cor,ctx,aucell} ...
 
-    Single-Cell rEgulatory Network Inference and Clustering (0.12.0)
+    Single-Cell rEgulatory Network Inference and Clustering (0.12.1)
 
     positional arguments:
       {grn,add_cor,ctx,aucell}
@@ -114,12 +114,12 @@ Docker/Podman images are available at `Docker Hub pySCENIC`_ and `Docker Hub pyS
 .. code-block:: bash
 
     # pySCENIC CLI version (recommended).
-    docker pull aertslab/pyscenic:0.12.0
-    podman pull docker://aertslab/pyscenic:0.12.0
+    docker pull aertslab/pyscenic:0.12.1
+    podman pull docker://aertslab/pyscenic:0.12.1
 
     # pySCENIC CLI version + ipython kernel + scanpy.
-    docker pull aertslab/pyscenic_scanpy:0.12.0_1.9.1
-    podman pull docker://aertslab/pyscenic_scanpy:0.12.0_1.9.1
+    docker pull aertslab/pyscenic_scanpy:0.12.1_1.9.1
+    podman pull docker://aertslab/pyscenic_scanpy:0.12.1_1.9.1
 
 To run pySCENIC using Docker/Podman, use the following three steps.
 A mount point (or more than one) needs to be specified, which contains the input data and necessary resources).
@@ -128,7 +128,7 @@ A mount point (or more than one) needs to be specified, which contains the input
 
     docker run -it --rm \
         -v /data:/data \
-        aertslab/pyscenic:0.12.0 pyscenic grn \
+        aertslab/pyscenic:0.12.1 pyscenic grn \
             --num_workers 6 \
             -o /data/expr_mat.adjacencies.tsv \
             /data/expr_mat.tsv \
@@ -136,7 +136,7 @@ A mount point (or more than one) needs to be specified, which contains the input
 
     docker run -it --rm \
         -v /data:/data \
-        aertslab/pyscenic:0.12.0 pyscenic ctx \
+        aertslab/pyscenic:0.12.1 pyscenic ctx \
             /data/expr_mat.adjacencies.tsv \
             /data/hg19-tss-centered-5kb-7species.mc9nr.genes_vs_motifs.rankings.feather \
             /data/hg19-tss-centered-10kb-7species.mc9nr.genes_vs_motifs.rankings.feather \
@@ -148,7 +148,7 @@ A mount point (or more than one) needs to be specified, which contains the input
 
     docker run -it --rm \
         -v /data:/data \
-        aertslab/pyscenic:0.12.0 pyscenic aucell \
+        aertslab/pyscenic:0.12.1 pyscenic aucell \
             /data/expr_mat.tsv \
             /data/regulons.csv \
             -o /data/auc_mtx.csv \
@@ -162,19 +162,19 @@ Singularity/Apptainer images can be build from the Docker Hub image as source:
 .. code-block:: bash
 
     # pySCENIC CLI version.
-    singularity build aertslab-pyscenic-0.12.0.sif docker://aertslab/pyscenic:0.12.0
-    apptainer build aertslab-pyscenic-0.12.0.sif docker://aertslab/pyscenic:0.12.0
+    singularity build aertslab-pyscenic-0.12.1.sif docker://aertslab/pyscenic:0.12.1
+    apptainer build aertslab-pyscenic-0.12.1.sif docker://aertslab/pyscenic:0.12.1
 
     # pySCENIC CLI version + ipython kernel + scanpy.
-    singularity build aertslab-pyscenic-scanpy-0.12.0-1.9.1.sif docker://aertslab/pyscenic_scanpy:0.12.0_1.9.1
-    apptainer build aertslab-pyscenic-0.12.0-1.9.1.sif docker://aertslab/pyscenic_scanpy:0.12.0_1.9.1
+    singularity build aertslab-pyscenic-scanpy-0.12.1-1.9.1.sif docker://aertslab/pyscenic_scanpy:0.12.1_1.9.1
+    apptainer build aertslab-pyscenic-0.12.1-1.9.1.sif docker://aertslab/pyscenic_scanpy:0.12.1_1.9.1
 
 
 To run pySCENIC with Singularity/Apptainer, the usage is very similar to that of Docker/Podman.
 
 .. code-block:: bash
 
-    singularity run aertslab-pyscenic-0.12.0.sif \
+    singularity run aertslab-pyscenic-0.12.1.sif \
         pyscenic grn \
             -B /data:/data
             --num_workers 6 \
diff --git a/docs/releasenotes.rst b/docs/releasenotes.rst
index 01a0f27..fc0e134 100644
--- a/docs/releasenotes.rst
+++ b/docs/releasenotes.rst
@@ -1,6 +1,13 @@
 Release Notes
 =============
 
+0.12.1 | 2022-11-21
+^^^^^^^^^^^^^^^^^^^
+
+* Add support for running arboreto_with_multiprocessing.py with spawn instead of fork as multiprocessing method.Pool
+* Use ravel instead of flatten to avoid unnecessary memory copy in aucell
+* Update Docker image file and add separated Docker file for pySCENIC with scanpy.
+
 0.12.0 | 2022-08-16
 ^^^^^^^^^^^^^^^^^^^
 
diff --git a/pyscenic_with_scanpy.Dockerfile b/pyscenic_with_scanpy.Dockerfile
index a9ff1ff..ebbad82 100644
--- a/pyscenic_with_scanpy.Dockerfile
+++ b/pyscenic_with_scanpy.Dockerfile
@@ -1,4 +1,4 @@
-FROM aertslab/pyscenic:0.12.0 AS compile-image
+FROM aertslab/pyscenic:0.12.1 AS compile-image
 
 ENV DEBIAN_FRONTEND=noninteractive
 
@@ -11,7 +11,7 @@ RUN apt-get update && \
 COPY requirements_docker_with_scanpy.txt /tmp/
 RUN pip install --no-cache-dir -r /tmp/requirements_docker_with_scanpy.txt
 
-FROM aertslab/pyscenic:0.12.0  AS build-image
+FROM aertslab/pyscenic:0.12.1 AS build-image
 
 RUN apt-get -y update && \
     apt-get -y --no-install-recommends install \