DESCRIPTION

Package: MRAPSS
Title: The MRAPSS package implement the MR-APPSS approach to test for the causal effect of an exposure on a outcome disease.
Version: 0.0.0.9000
Authors@R: 
    person(given = "Xianghong",
           family = "HU",
           role = c("aut", "cre"),
           email = "maxhu@ust.hk",
           comment = c(ORCID = "0000-0001-5260-3936"))
Description: The MRAPSS package implement the MR-APPSS approach to test for the causal effects between an exposure and a outcome disease.
        The MR-APPSS is a unified approach to Mendelian Randomization accounting for polygenicity, pleiotropy and sample structure using genome-wide summary statistics.
        Specifically, MR-APPSS uses a background-foreground model to characterize both SNP-exposure effects and SNP-outcome effects estimates, where the background model accounts for confounding from genetic correlation and sample structure and the foreground model captures the valid signal for causal inference.
License: What license it uses
Encoding: UTF-8
LazyData: true
Imports:
    ggplot2,
    ggnewscale,
    dplyr,
    magrittr,
    ieugwasr (>= 0.1.4),
    readr,
    expm
Remotes:
    mrcieu/ieugwasr
RoxygenNote: 7.0.2
Depends: 
    R (>= 2.10)
Suggests: 
    knitr,
    rmarkdown
VignetteBuilder: knitr