The goal of mpraprofiler is to create a simple tool to perform allelic differential expression analysis for massively parallel reporter assay (MPRA) data.
You can install mpraprofiler from GitHub with:
install.packages("devtools") # if not already installed
devtools::install_github("WeirauchLab/mpraprofiler")To build the vignette(s), install some additional packages
install.packages("tidyverse")
install.packages("readxl")
# You'll need Bioconductor to get DESeq2
install.packages("BiocManager")
BiocManager::install('DESeq2')…and add build_vignettes = TRUE to the install command:
devtools::install_github("WeirauchLab/mpraprofiler", build_vignettes = TRUE,
force = TRUE)Please refer to
vignettes/sample_analysis.md for
details.
Xiaoming Lu, mpraprofiler, (2020), GitHub repository, https://github.com/WeirauchLab/mpraprofiler
| Name | Institution | Remarks |
|---|---|---|
| Dr. Xiaoming Lu | Cincinnati Children’s Hospital | primary author |
| Kevin Ernst | Cincinnati Children’s Hospital | minor documentation and packaging fixes |
Copyleft Cincinnati Children’s Hospital Medical Center and contributors.
Released under the terms of the GNU General Public License v3. See
LICENSE.md for details.