PaSM: Parameter Space Mapping algorithms for QSP applications

PaSM is a package created to accelerate the creation of plausible Virtual Patient (VP) by exploiting monotonic parameter information.

Manuscript

A manuscript detailing the methodology and evaluating PaSM performance was published on JPKPD. A temporary free access to the article is also available here. All the source code used in the paper (model equations, figure scripts...) are available in the article_resources subfolder.

Installation:

To install the package, please use the following code in your R session:

   devtools::install_github("Thibaudpmx/PaSM")

Tutorial/Documentation

A quick tutorial has been produced to use the package, please click here to download.

Reporting bug issues

To report any bug issues or suggest new featuring, please contact me at thibaud.derippe@gmail.com or create an issue on GitHub.

Thanks !