Skip to content

Commit

Permalink
minor fix
Browse files Browse the repository at this point in the history
  • Loading branch information
buddekai committed Jul 21, 2020
1 parent d7830cf commit 1668b72
Show file tree
Hide file tree
Showing 2 changed files with 3 additions and 3 deletions.
2 changes: 1 addition & 1 deletion README.md
Original file line number Diff line number Diff line change
@@ -1,5 +1,5 @@
# SI_LRP6_Endocytosis_Model
Supporting information for the paper by F. Haack, K. Budde, and A. M. Uhrmacher: "Exploring mechanistic and temporal regulation of LRP6 endocytosis in canonical WNT signaling", Journal of Cell Science (2020), doi: 10.1242/jcs.243675.
Supporting information for the paper by F. Haack, K. Budde, and A. M. Uhrmacher: "[Exploring mechanistic and temporal regulation of LRP6 endocytosis in canonical WNT signaling](https://doi.org/10.1242/jcs.243675)", Journal of Cell Science (2020).

## General information
This README briefly explains the content of the subdirectories and how to replicate all experiments and obtain the figures shown in the paper mentioned above.
Expand Down
4 changes: 2 additions & 2 deletions data/README.md
Original file line number Diff line number Diff line change
Expand Up @@ -5,11 +5,11 @@ The data found in the files were taken from literature (see below) and are used
## DKK_Endocytosis.csv

**What:** The data has been taken from Fig. 3C of [16] by using the pixel coordinates of the mean and s.e.m. Regarding the data: "The amounts of cell-surface or total LRP6 were quantified using NIH image software. The results are shown as the ratio of cell-surface LRP6 to total LRP6. Values at zero time were set to 100%. The results shown are means ± s.e.m. from four independent experiments." [16]
**Reference:** [16] Hiroshi Sakane, Hideki Yamamoto, and Akira Kikuchi. Lrp6 is internalized by dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse. J Cell Sci, 123:360–368, 2010.
**Reference:** [16] Hiroshi Sakane, Hideki Yamamoto, and Akira Kikuchi. [Lrp6 is internalized by dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse](https://doi.org/10.1242/jcs.058008). J Cell Sci, 123:360–368, 2010.


## RawDataSurfaceLRP6.csv

**What:** The data has been taken from Fig. 1C of [11] by using the pixel coordinates of the mean and s.e. Regarding the data: "The amounts of cell surface or total LRP6 were analyzed with NIH images. The results are expressed as the ratio of cell surface LRP6 to total LRP6 (lower panel). Values at zero times are set to 100%. The results shown are means ± SE from three independent experiments."
experiments." [16]
**Reference:** [11] Hideki Yamamoto, Hideyuki Komekado, and Akira Kikuchi. Caveolin is necessary for wnt-3a-dependent internalization of lrp6 and accumulation of b-catenin. Dev. Cell., 11(2):213–223, 2006.
**Reference:** [11] Hideki Yamamoto, Hideyuki Komekado, and Akira Kikuchi. [Caveolin is necessary for Wnt-3a-dependent internalization of Lrp6 and accumulation of β-catenin](https://doi.org/10.1016/j.devcel.2006.07.003). Dev. Cell., 11(2):213–223, 2006.

0 comments on commit 1668b72

Please sign in to comment.