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@adeschen adeschen released this 29 Sep 22:25
· 103 commits to main since this release
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The Robust Ancestry Inference using Data Synthesis (RAIDS) package enables accurate and robust inference of genetic ancestry from various types of molecular data, including whole-genome, whole-exome, targeted gene panels and RNA sequences, as described in our manuscript. Our tools retain high accuracy in presence of somatic alterations, such as those caused by cancer.

This code and analysis pipeline were designed and developed for the following publication:

Pascal Belleau, Astrid Deschênes, Nyasha Chambwe, David A. Tuveson, Alexander Krasnitz; Genetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms. Cancer Res 1 January 2023; 83 (1): 49–58. https://doi.org/10.1158/0008-5472.CAN-22-0682

SIGNIFICANT USER-VISIBLE CHANGES

o Seven new loadable objects are available in the package.
o The new readSNVVCF() function enable the use of VCF SNP files as input for the runExomeAncestry() and runRNAAncestry() functions.