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Immunotherapy Genomic Biomarkers

Users should be able to input mutation/expression data and get the resulting features defined

Input files:

  1. Genomic mutation data (MAF)
  2. Gene expression matrix

Study approach:

  1. Compile treatments, indications, biomarkers, reference in a table
  2. Make each score/feature using multi-omics data of TCGA
  3. Combine and study correlation of all features / correcting for phenotype / predict survival
Treatment type Biomarker Indication Reference Status
xx PD1 level Content Cell Content Cell Content Cell
test PD-L1 level Content Cell Content Cell Content Cell
xx Tumor Mutational Burden (TMB) Content Cell Content Cell Content Cell
test ?? Content Cell Content Cell Content Cell