DrugReSC

Package development by:
Chonghui Liu (18845077529@163.com)
Guohua wang (ghwang@nefu.edu.cn)

Introduction

DrugReSC, an innovative approach to drug repurposing utilizing single-cell RNA sequencing data, with the objective of targeting specific cell subpopulations critical to disease pathology.

Installation

• Step 1 Install devtools in R

install.packages("devtools")

• Step 2 Install DrugReSC in R

library(devtools)
install_github("Chonghui-Liu/DrugReSC")

Examples

Please see https://htmlpreview.github.io/?https://github.com/Chonghui-Liu/DrugReSC/blob/main/vignettes/DrugReSC%20Tutorial.html for details. In the R terminal, please use the command ?DrugReSC to access the help documents.

How to cite DrugReSC

Please cite the following manuscript:

DrugReSC: Targeting disease-critical cell subpopulations with single-cell transcriptomic data for drug repurposing in cancer. Chonghui Liu, Yan Zhang, and Guohua Wang

Support

If you have any question regarding the use of DrugReSC, feel free to submit an issue. Improvements and new features of DrugReSC will be updated on a regular basis.